| Message: | Dihydrotestosterone (DHT), or 5α-dihydrotestosterone (5α-DHT), also known as 5α-androstan-17β-ol-3-one, is anendogenous androgen sex steroid and hormone. The enzyme 5α-reductase catalyzes the formation of DHT fromtestosterone in certaintissues including the prostate gland, seminal vesicles, epididymides, skin, hair follicles,liver, and brain. This enzyme mediates reduction of the C4-5 double bond of testosterone. Relative to testosterone, DHT is considerably more potent as an agonist of the androgen receptor(AR).
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