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17alpha-Estradiol
Alias: Epiestradial; 17a-Estradiol (8CI); 1, 3, 5-Estratriene-3, 17a-diol; 13b-Methyl-1, 3, 5(10)-gonatriene-3, 17a-diol; 17-Epiestradiol; 17a-Oestradiol; 3, 17-Dihydroxyestratriene; 3, 17a-Dihydroxyestra-1, 3, 5(10)-triene; 3, 17a-Dihydroxyoestra-1, 3, 5(10)-triene; Alfatradiol; Epiestrol; Estra-1, 3, 5(10)-triene-3, 17a-diol; NSC 20293; Oestra-1, 3, 5(10)-triene-3, 17a-diol; A-Estradiol;
Purity: 99% min.
CAS Registry Number: 57-91-0
Einecs No: 200-354-8
MF: C18H24O2
MW: 272.38
Purity: 99%
Appearance: White Solid
Melting point: 176-180º C.
Density: 1.17 g/cm3
Boiling Point: 445.9 ° C at 760 mmHg
Melting Point: 176-180 ° C(lit. )
Flash Point: 209.6 ° C
Storage Temperature: 0-6° C
Refractive index: 1.599
Solubility: Ethanol: 50 mg/mL, clear, colorless
3. Application:
17alpha-Estradiol (known as α -Estradiol or 17 α -Estradiol) is a biologically active estrogen in human breast cancer cells in tissue culture. 17alpha-Estradiol and its selective receptor, ER-X, are not part of a classical hormone/receptor endocrine system but of a system with important autocrine/paracrine functions in the developing and adult brain. 17alpha-Estradiol may have enormous implications for hormone replacement strategies at the menopause and in the treatment of such neurodegenerative disorders as Alzheimer's disease and ischemic stroke. |
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