| Message: | Gonadorelin, 2mg/vial, 10mg/vial
Product Name Gonadorelin Acetate
Sequence Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2
Cas No. 71447-49-9
Molecular Formula C55H75N17O13
Molecular Weight 1182.3
Purity (HPLC) 98.0%min.
Appearance White powder
Single Impurity(HPLC) 0.5%max
Amino Acid Composition ±10% of theoretical
Peptide Content(N%) ≥80.0%
Water Content(Karl Fischer) ≤8.0%
Acetate Content(HPIC) ≤10.0%
Specific Rotation (20/D) -55.0～-65.0°(c=1 1%HAc)
MS(ESI) Consistent
Mass Balance 95.0~105.0%
Gonadorelin is another name for gonadotropin-releasing hormone (GnRH). It is a synthetic decapeptide prepared using solid phase peptide synthesis. GnRH is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pitutitary.
GnRH is available as gonadorelin hydrochloride )and gonadorelin diacetate tetrahydrate for injectable use. Studies have described it being used via an infusion pump system to induce ovulation in patients with hypothalamic hypogonadism. It is also used in veterinary medicine as a treatment for cattle with cystic ovarian disease.
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