| Message: | 99% Oral & Injectable Progestogen for Gynaecological Conditions Dydrogesterone CAS 152-62-5
1. Quick Detail:
Product Name Dydrogesterone
Alias terolut; dufaston; gynorest; diphaston; duvaron
CAS 152-62-5
EINECS 205-806-8
Assay 99.0%
Appearance white to off-white crystalline powder
Molecular Formula C21H28O2
Molecular Weight 312.45
Grade Pharmaceutical Grade
Storage Shading, Confined Preservation
Brand Name NJBN STEROIDS
2. Description:
Dydrogesterone is a steroidal, pure progestin that was developed in the 1950s. Dydrogesterone has selective progestational activity and does not inhibit ovulation. The greater rigidity of dydrogesterone also positively affects its selectivity, while natural progesterone is less selective, existing in different conformations that more easily bind to different receptors. As a consequence of its better bioavailability and the progestational activity of its main metabolites (20-, 21- and 16-hydroxy derivatives), the equivalent dose of dydrogesterone is 10–20 times lower than that of oral micronized progesterone.
3. Application:
Dydrogesterone is used as an effective, orally active progestogen for gynaecological conditions related to a wide variety of progesterone deficiencies in pregnant women. The molecular structure and pharmacological effects are somewhat similar to endogenous progesterone, although in smaller amounts it is found to be orally active. Its freedom from hormonal effects like those related to corticoid, androgenic, estrogenic, anabolic, and other effects gives dydrogesterone an advantage over other synthesized progestogens.
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