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Anamorelin

Create: 09/28/2016
Expired Date:09/30/2019
Category: Estrone [Health&Medical&Pharmaceutical]
Message: Anamorelin(RC1291; ONO-7643) is a synthetic orally active ghrelin receptor agonist which is under development for the management of non-small lung cancer associated cachexia/anorexia. Cas:249921-19-5 MW:546.7 MF:C31H42N6O3 The solvent/solubility: 10 mM in DMSO IC50 Value: Target: GHSR Anamorelin hydrochloride is the orally bioavailable hydrochloride salt of a synthetic, small-molecule ghrelin mimetic with appetite-stimulating and anabolic activities. Anamorelin binds to and stimulates the growth hormone secretagogue receptor (GHSR) centrally, thereby mimicking the appetite-stimulating and growth hormone-releasing effects of grhelin. Stimulation of GHSR may also reduce the production of the pro-inflammatory cytokines TNF-alpha and interleukin-6, which may play a direct role in cancer-related loss of appetite.
City:Wuhan Hubei[CN] 
Location:
 
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