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Synonyms: Ibutamoren, CHEMBL13817, S1151_Selleck, MK-677
CAS No.: 159752-10-0
Molecular Weight: 624.77
Molecular Formula: C28H40N4O8S2
Purity: 99%
Description:
Ibutamoren (MK-0677) is a revolutionary non-peptide growth hormone (GH) secretagogue. MK-0677
triggers GH pulse discharge through the pituitary and hypothalamic receptors mimicking the GH
stimulating action of the endogenous hormone ghrelin. It has been widely demonstrated to upsurge
the release of, and creates sustained increases in plasma levels of several hormones including growth
hormone and IGF-1, but without affecting cortisol levels. It is currently under development as a potential
treatment for reduced levels of these hormones, such as in growth hormone deficient children or elderly
adults, and human studies have shown it to increase both muscle mass and bone mineral density,
making it a promising therapy for the treatment of frailty in the elderly. MK-0677 also alters basal
metabolism of body fat and so may have application in the future treatment of obesity."
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