| Message: | Econazole;1-[2-[(4-Chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
Econazole;1-[2-[(4-Chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
Molecular formula : C18H15Cl3N2O
MW : 381.68
CAS No. :27220-47-9
nature : 86.8 ° C melting point. Its nitrate ([24169-02-6]) melting point of 162 ° C and water-soluble.
Preparation Methods : 10.3 in the α - (2,4-dichlorophenyl) - imidazole-1-ethanol and 2.1 in sodium hydride 50 anhydrous tetrahydrofuran the slurry mixing returning 2h, when hydrogen reaction after successive accession 60 dimethyl formamide and 8-chloro-benzyl chloride to return 2h. Tetrahydrofuran pressure steam addition, the residues dumped into the water with benzene extraction, extracts from decompression benzene, in econazole in the free base, and then concentrated nitric acid, generating econazole nitrate.
purposes : the first generation of products imidazole antifungal agents.
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