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Anti-Ccnd1 immunotoxin (IgG)-RTA

Create: 02/27/2017
Expired Date:02/16/2021
Category: Drugs&Pharmaceutical [Health&Medical&Pharmaceutical]
Message:This immunotoxin was achieved by conjugating/fusing the Anti-Ccnd1 monoclonal antibody to ricin toxin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to B cell tumor cells. Then the ricin A chain is incorporated into the cell by receptor-mediated endocytosis, blocking ribosomal protein synthesis and ultimately leading to cell death. It was designed for treatment of B cell tumor.
City:Shirley[US] 
Location:
 
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