Message: | Raw Biochemical Material Mannitol
Product Name: Mannitol
Alias: D-Mannitol,Diosmol,Manicol,Manita,Manna Sugar
CAS: 69-65-8
EINECS: 200-711-8
MF: C6H14O6
MW: 182.17
Purity: 99%
Grade: Pharmaceutical Grade
Appearance: White Powder
Usage: Pharmaceutical Raw Materials
Mannitol (also referred to as mannite or manna sugar) is a white, crystalline solid that looks and tastes sweet like sucrose. It was originally isolated from the secretions of the flowering ash and called manna after its resemblance to the Biblical food. In plants it is used to alleviate osmotic stress. Mannitol has several industrial uses, but is mainly used to produce tablets of medicine. Mannitol is classified as a sugar alcohol; that is, it is derived from a sugar (mannose) by reduction. Other sugar alcohols include xylitol and sorbitol. Mannitol and sorbitol are isomers, the only difference being the orientation of the hydroxyl group on carbon 2.
Mannitol is used clinically in osmotherapy to reduce acutely raised intracranial pressure until more definitive treatment can be applied, e.g., after head trauma. It is also used to treat patients with oliguric renal failure. Intravenous mannitol opens the blood-brain barrier to hydrophilics by stretching the tight junctions between the endothelial cells.
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