| Message: | Andriol first became available in the early 1980s. This compound contains 40 mg of testosterone undecanoate, based in oil (oleic acid) and sealed inside a capsule.
Subtracting the ester weight, this equates to a dosage of approximately 25mg of raw testosterone per cap. The design of this steroid is quite different from that of most oral steroids.
Drugs administered orally generally enter the blood stream through the liver. When a steroid compound is given this way without some form of structural protection, it will be quickly broken down during the "first pass".
This process leaves very little steroid intact, basically deactivating the drug. Adding a methyl group (c-17 AA) to the structure is one way to protect it from this process, however stress is also placed on the liver as a result.
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