my account  log out
 

transferrin-Sap immunotoxin

Create: 03/30/2017
Expired Date:03/08/2019
Category: Drugs&Pharmaceutical [Health&Medical&Pharmaceutical]
Message:This immunotoxin was achieved by conjugating/fusing the transferrin to saporin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to TFRC expressing cells and enters cells by receptor-mediated endocytosis. Upon release of the conjugate from endosomes, the saporin toxin catalytically renders the large subunit ribosomes unable to bind the elongation factors and inhibits protein synthesis. It was designed for treatment of T cell leukemias or lymphomas, graft-versus-host diseases, and autoimmune diseases.
City:Shirley[US] 
Location:
 
Feb 01 2023 VBS++ (with Ca and Mg) Buffer232
Feb 01 2023 GVBE Buffer232
Feb 01 2023 GVB++ (with Ca and Mg) Buffer239
Feb 01 2023 Hemolysin (Rabbit Anti-Sheep Cell Hemolysin)227
Aug 30 2019Anti-HSV-2 gH Antibody420
Aug 30 2019Anti-L. major LPG Antibody501
Aug 30 2019Anti-DENV-1 Antibody410
Aug 30 2019Anti-BPV-1 L1 Antibody427
Aug 30 2019Anti-H3N2 HA Antibody408
Aug 30 2019Anti-EIAV env Antibody435

return back

Copyright © toextrade Inc. All rights reserved. Contact us