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Bispecific IGFR/CD3 BiTE

Create: 04/24/2017
Expired Date:04/02/2026
Category: Drugs&Pharmaceutical [Health&Medical&Pharmaceutical]
Message:This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
City:Shirley, NY[US] 
Location:
 
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