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Product name: Procaine
Alias: Procaine hydrochloride; Aminocaine; Anadolor; Atoxicocaine;
CAS register number: 59-46-1
Molecular formula: C13H21ClN2O2
Molecular weight: 236.31
Appearance: White crystalline powder
Description:
Procaine hydrochloride, also called Novocain, synthetic organic compound used in medicine as a local anesthetic. It became the first and best-known substitute for cocaine in local anesthesia. Generally used in a 1 to 10 percent saline solution, procaine hydrochloride is administered by injection for infiltration (area flooding as in dental anesthesia), nerve-block, spinal, and caudal anesthesia. Unlike cocaine, procaine is not toxic, addicting, or irritating. It has been displaced somewhat by the chemically related drugs lidocaine and mepivacaine, which produce prompter, more intense anesthesia.
Procaine HCl is indicated for the production of local or regional analgesia and anesthesia by local infiltration and peripheral nerve block techniques.
The routes of administration and concentrations are: for local infiltration use 0.25% to 0.5% (via dilution) and for peripheral nerve blocks use 0.5% (via dilution), 1%, and 2%. (See DOSAGE AND ADMINISTRATION for additional information.)
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