| Message: | Product Name	Memantine HCL
Memantine HCL Alias	Memantine Hydrochloride
Memantine HCL CAS	41100-52-1
Memantine HCL EINECS	255-219-6
Memantine HCL MF	C12H22ClN
Memantine HCL MW	215.7628
Memantine HCL Purity	99%
Memantine HCL MP	292 °C
BP	239.8°C at 760 mmHg
FP	92.3°C
Grade	Pharmaceutical Grade
Appearance	White Crystalline
Memantine HCL is an oral medication for the treatment of moderate to severe dementia associated with Alzheimer's. Memantine HCL's effects are independent of acetylcholine and acetylcholinesterase.
It is believed that too much stimulation of nerve cells by glutamate may be responsible for the degeneration of nerves that occurs in some neurological diseases such as Alzheimer's disease. Glutamate is produced and released by nerve cells in the brain. The released glutamate then travels to nearby nerve cells where it attaches to a receptor on the surface of the cells called the N-methyl-D-aspartate (NMDA) receptor.
Memantine HCL blocks this receptor and thereby decreases the effects of glutamate. It is thought that by blocking the NMDA receptor and the effects of glutamate, memantine may protect nerve cells from excess stimulation by glutamate. |