| Message: | Cabergoline / Caber CAS: 81409-90-7
Product Name: Cabergoline
Synonyms: Dostinex ; Cabaser ; Caber
CAS: 81409-90-7
MF: C26H37N5O2
MW: 451.6
mp: 102-104°C
storage temp: Store at +4°C
Appearence: White Crystalline Solid
Usage:
1. hyperprolactinemia
2. adjunctive therapy of prolactin-producing pituitary gland tumors (prolactinomas)
3. monotherapy of Parkinson's disease in the early phase
4. combination therapy, together with levodopa and a decarboxylase inhibitor such as carbidopa, in progressive-phase Parkinson's disease
5. ablactation and dysfunctions associated with hyperprolactinemia (amenorrhea, oligomenorrhea, anovulation, nonpuerperal mastitis and galactorrhea)
6. treatment of uterine fibroids
7. adjunctive therapy of acromegaly, cabergoline has low efficacy in suppressing levels and is highly efficient in suppressing hyperprolactinemia that is present in 20-30% of acromegaly cases
8.and prolactin are similar structurally and have similar effects in many target tissues, therefore targeting prolactin may help symptoms when hormone secretion can not be sufficiently controlled by other methods
9. Cushing's disease - cabergoline may be used to lower ACTH levels and cause regression of ACTH producing pituitary adenomas
10. other pituitary adenomas - cabergoline has demonstrated certain efficacy in controlling or reducing other kinds of pituitary adenomas, as well as silent or non-functional adenomas
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