| Message: | GW501516 (also known as GW-501,516, GW1516, GSK-516) is a PPARδ receptor agonist that was invented in a collaboration between Ligand Pharmaceuticals and GlaxoSmithKline in the 1990s, was entered into clinical development as a drug candidate for metabolic diseases and cardiovascular diseases, and was abandoned in 2007 because animal testing showed that the drug caused cancer to develop rapidly in several organs.
In 2007 research was published showing that high doses of GW501516 given to mice dramatically improved their physical performance; the work was widely discussed in popular media, and led to a black market for the drug candidate and to its abuse by athletes as a doping agent.
GW-501516 Uses:
GW-501516 has many benefits but has two primary uses. The most common use of GW consists of the extreme amount of endurance and recovery increase.
The other main use of GW-501516 is to aid in fat loss. GW-501516 has shown to melt away fat at a rapid pace.
GW-501516 Dosing Timing:
GW-501516 also has a very long half life, so it can be dosed once a day or split 12 hours apart. The most effective method of dosing is to take it in one serving, 30 minutes prior to working out. On non workout days, once a day dosing in the morning is the best method. If a split dosage is used, 10-12 hour splits are optimal. |
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