Message: | A Potential Treatment for Skin Cancer:
It is known that the effects of α-MSH are mediated by melanocortin receptors.
MC1R is expressed in skin cells and has a high affinity for α-MSH and is the main receptor by which α-MSH signals.
Based on this fundamental information and observations of how α-MSH impacts melanomic cells, one study has hypothesized that "α-MSH acts initially to reduce initial tumor spread, but paradoxically protects those cells that escape from the primary tumor.
As an analog of α-MSH, it is logical to believe that Melanotan II may have similar effects. |