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ARE Reporter Kit (Nrf2 Antioxidant Pathway )

Create: 12/17/2018
Expired Date:never
Category: Diagnostic equipment [Health&Medical&Pharmaceutical]
Message:The Nrf2 antioxidant response pathway plays an important role in the cellular antioxidant defense. Nrf2, a basic leucine zipper transcription factor, induces the expression of antioxidant and phase II enzymes by binding to the ARE (antioxidant response element) region of the gene promoter. Under basal conditions, Nrf2 is retained in the cytosol by binding to the cytoskeletal protein Keap1. Upon exposure to oxidative stress and other ARE activators, Nrf2 is released from Keap1 and translocates to nucleus, where it can bind to the ARE, leading to the expression of antioxidant and phase II enzymes that protect the cell from oxidative damage. https://www.creativebiomart.net/are-reporter-kit-nrf2-antioxidant-pathway-465565.htm
City:[US] 
Location:
 
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