| Message: | Tadalafil is one of the more popular erectile dysfunction (ED) medications on the market and is most commonly associated with the brand name Cialis. Cialis is very similar to the popular ED medication Viagra with the biggest difference being the drug's active life. Cialis will produce erections for 36-48 hours from one single dose where Viagra is limited to 4-6 hours from one single dose. Cialis is also prescribed for the treatment of BPH (Benign Prostatic Hyperplasia), which refers to an enlarged prostate that results in difficulty or frequent urination.
Tadalafil improves erectile function significantly, possibly increase testosterone through increased sexual activity, and is very safe.Although and tadalafil all work by inhibiting PDE5, tadalafil's pharmacologic distinction is its longer half-life (17.50 hours) - compared to sildenafil (4.0-5.0 hours) and vardenafil (4.0-5.0 hours) - resulting in longer duration of action, and so partly responsible for "The Weekend Pill" sobriquet.
Furthermore, the longer half-life is the basis for current investigation of tadalafil's daily therapeutic use in relieving pulmonary arterial hypertension. approved in several world regions as a thrice-daily therapy for pulmonary arterial hypertension.
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