| Message: | Malate dehydrogenase (MDH) is one of the key enzymes in glycometabolism, which can catalyze the reversible conversion between malic acid and oxaloacetic acid. MDHS play an important role in many physiological activities of cells, including energy metabolism of mitochondria and active oxygen metabolism of plants.
The optimum pH value of MDHS was about 8.0. For example, the enzyme activity of Streptomyces and Escherichia coli was the highest at pH 8.1. The optimum reaction temperature was 40 ~ 65 ℃. For example, the optimum temperature of MDH of Bacillus subtilis and myocardial MDH of pig is about 50 ℃, and the stability of Bacillus stearothermophilus (bmdh) is better at 65 ℃. The MDHS activity of most species is not high when the temperature tends to the two poles. However, the MDH from psychrophilic bacteria (aamdh) remains high at about 4 ℃, and that of thermophilic bacteria can remain about 1 h at 90 ℃. This difference may be due to the preference of some residues in the active site, the distribution of the charge of substrate and cofactor, and the interaction of ion pairs between subunits It is caused by the function and other reasons.
Desheng is a professional manufacturer of malate dehydrogenase, which can produce a variety of enzyme products. The enzyme products provided are mainly used as raw materials for kit detection, and the appearance of raw materials is freeze-dried powder, which is higher than the industrial level enzyme activity. Company in the transportation process will be equipped with ice bag transportation, to ensure the enzyme activity of products, welcome to consult and purchase! |
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