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This has to do with the way GW 501516 works.
GW 501516 is a selective agonist of the PPARδ receptor -- which actually explains the relationship between GW 501516 and SARMs. GW 501516 is not belonged to SARM (selective androgen receptor agonists).
PPAR is a class of ligand-dependent nuclear transcription factors important for metabolic homeostasis. PPARδ is one of three types of PPARs expressed in adipose tissue, liver, skin, brain and skeletal muscle.
PPARδ regulates many different biological activities such as lipid and lipoprotein metabolism, mitochondrial respiration, skeletal muscle reorganization.It also incldue thermogenesis, inflammation, keratinization , cell differentiation , and wound healing .
Normal bodybuilding is to promote protein catabolism and gluconeogenesis to provide energy needed for bodybuilding. But GW 501516, as a selective agonist of PPARδ receptor, regulates lipid and protein metabolism. The energy required for bodybuilding is provided by increasing the specific consumption of fatty acids.
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