| Message: | Product Description:
Estradiol is a type of estrogen, the major sex hormone in women. It is secreted by the ovarian follicles. As the follicles grow and develop each month, they produce estradiol. This sets the rest of the reproductive cycle in motion.
Estradiol is a form of estrogen, a female sex hormone that regulates many processes in the body.
Estradiol transdermal skin patches are used to treat certain symptoms ofmenopause such as hot flashes, and vaginal dryness, burning, and irritation. This medication is also used to prevent postmenopausalosteoporosis, or to treat ovarian disorders.Estradiol transdermal may also be used for purposes not listed in this medication guide.
Application:
1.Female reproduction:
In the female, estradiol acts as a growth hormone for tissue of the reproductive organs, supporting the lining of the vagina, the cervical glands, theendometrium, and the lining of the fallopian tubes. It enhances growth of the myometrium. Estradiol appears necessary to maintain oocytes in the ovary. During the menstrual cycle, estradiol produced by the growing follicle triggers, via a positive feedback system, the hypothalamic-pituitary events that lead to theluteinizing hormone surge, inducing ovulation. In the luteal phase, estradiol, in conjunction with progesterone, prepares the endometrium for implantation. During pregnancy, estradiol increases due to placental production. In baboons, blocking of estrogen production leads to pregnancy loss, suggesting estradiol has a role in the maintenance of pregnancy. Research is investigating the role of estrogens in the process of initiation of labor. Actions of estradiol are required before the exposure of progesterone in the luteal phase.
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