| Message: | Dextromethorphan Hydrobromide
Alias: Romilar,dextromethorphan,Demorphine,Dormetan
CAS No.: 125-69-9
EINECS No.: 204-750-1
MF: C18H26BrNO
MW: 352.31
Purity: 98.0%
Appearance: White or kind of white crystalline powder, soluble in water.
Dextromethorphan has also found other uses in medicine, ranging from pain relief to psychological applications. It is sold in syrup, tablet, spray, and lozenge forms. In its pure form, dextromethorphan occurs as a white powder.
DXM is also used recreationally. When exceeding label-specified maximum dosages, dextromethorphan acts as a dissociative hallucinogen.
Its mechanism of action is via multiple effects, including actions as a nonselective serotonin reuptake inhibitor and a sigma-1 receptor agonist. The major metabolite of DXM, dextrorphan, also acts as an NMDA receptor antagonist. In high doses this produces effects similar to, yet distinct from, the dissociative states created by other dissociative anaesthetic .
As well, the metabolite 3-methoxymorphinan of dextrorphan (thus a second-level metabolite of DXM) produces local anesthetic effects in rats with potency above dextrorphan.
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