| Message: | Product Name: GLP-1 (7-37) Acetate
Alias: 7-37-Glucagon-likepeptide I (human);Glucagon-relatedpeptide 1 (Rana catesbeiana)
CAS: 106612-94-6
MF: C151H228N40O47
MW: 3355.74
Purity: 98.0%
Grade: Pharmaceutical Grade
Appearance: White Powder
Single Impurity (HPLC): 1.0%
Amino Acid Composition: 10% of theoretical
Peptide Content (N%): 80% (by %N)
Water Content (Karl Fischer): 6.0%
Acetate Content (HPIC): 15.0%
Storage: Closed, below 2 ~ 8℃ preservation
Manufacturer: Hezhong
Usage: GLP-1 can obviously improve the blood glucose in type 2 diabetes animal models or patients through a variety of mechanisms, which promote the regeneration and repair of islet beta cells, increase the number of beta cells is particularly significant role, provides a very good prospect for the treatment of type 2 diabetes mellitus.
Description
Glucagon like peptide -1 (GLP-1) is a brain gut peptides secretion ileal endocrine cells, at present mainly as a target for type 2 diabetes drug action. Because GLP-1 can reduce the inhibition of gastric emptying, intestinal peristalsis, thus helps to control food intake, weight loss. Prospective placebo in 19 cases of obese patients in control, random, double-blind, crossover trial, GLP-1 subcutaneous injection can increase the patients with postprandial satiety, and make each meal diet weight average reduction of 15%. But because GLP-1 is a polypeptide, cannot be administered orally is a major shortcoming.
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