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CAS 68-96-2 17alpha-Hydroxyprogesterone

Create: 12/21/2016
Expired Date:12/20/2017
Category: Raw materials [Health&Medical&Pharmaceutical]
Message:CAS 68-96-2 17alpha-Hydroxyprogesterone Product Name: 17A-Hydroxyprogesterone CAS: 68-96-2 EINEC: 200-699-4 MF: C21H30O3 MW: 330.4611 Assay: 99% Melting Point: 276 ℃ Appearance: White Or White Crystalline Powder Packaging: 1kg/bag Density: 1.15g/cm3 Boiling Point: 482.9℃ at 760 mmHg Flash Point: 259.9℃ Steam Pressure: 2.37E-11mmHg at 25℃ Usage: it is an important intermediate for the synthesis of steroid hormone and steroid progesterone drug. It can be synthesized by hydrocortisone, betamethasone, cortisone acetate, progesterone caproate, chlormadinone etc. The 17-hydroxyprogesterone (17-OHP) test is routinely ordered as part of newborn screening in the UnitedStates to detect congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency. CAH is a group ofinherited disorders caused by specific gene mutations and associated with cortisol-related enzymedeficiencies. About 90% of CAH cases are caused by a mutation in the 21-hydroxylase gene (also calledP450c1 or CYP21A2) and may be detected due to the accumulation of 17-OHP in the blood. The 17-OHP test may be used to screen for CAH in older children or adults before symptoms appear or toconfirm a CAH diagnosis in people with symptoms.
City:Jinan Shandong[CN] 
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