| Message: | Levothyroxine sodium; L-Thyroxine Sodium (Steroids)
Aliases: L-Thyroxine sodium salt; Sodium 4-o-(4-hydroxy-3, 5-diiodophenyl)-3, 5-diiodo-l-tyrosine; Sodium (2S)-2-amino-3-[4-(4-hydroxy-3, 5-diiodophenoxy)-3, 5-diiodophenyl]propanoate hydrate (1: 1: 5); Sodium 2-amino-3-[4-(4-hydroxy-3, 5-diiodophenoxy)-3, 5-diiodophenyl]propanoate; Tyrosine, O-(4-hydroxy-3, 5-diiodophenyl)-3, 5-diiodo-, sodium salt (1: 1)
CAS: 55-03-8
Appearance: Almost whtie powder
EINECS: 200-221-4
MF: C15H11I4NNaO4
MW: 799.8592
Weight Loss Chemical Raw Material CAS 25416-65-3 Levothyroxine Sodium / T4
Specifications:
Appearance: White crystals, crystalline powder
Assay: 99.0 - 100.5%
Specific Rotation: -0.10 o --- +0.10 o
Residue on ignition: 0.10% max
Water-insoluble substance: 0.1% max
Fumaric Acid: 1.0% max
Maleic Acid: 0.05% max
Heavy metals(as Pb): 10 ppm max
Arsenic(As): 4 ppm max
Boiling Point: 576.3 deg; C at 760 mmHg
Melting Point: 207-210 (DEC. )(lit. )
Flash Point: 302.3 deg; C
Storage Temperature: 2-8 deg; C
Solubility: Cell culture medium: 0.1 mg/mL in water
Usage: One of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia.
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