| Message: | Hydroxypropyl-beta-cyclodextrin is the hydroxyalkylated derivative of beta- cyclodextrin. Hydroxypropyl-beta-cyclodextrin is non-toxic and has no side effect, and it can significantly improve the solubility of insoluble drugs to dissolve insoluble or poorly water-soluble drugs due to its structural particularity. Therefore, it can effectively increase bioavailability of drugs; it can also improve drug quality and variety of dosage forms, thereby being applied in development and production of new drugs. Globally, in-depth studies of the properties, preparation technology, stability, pharmacology, toxicology, teratogenic, mutagenic, carcinogenic, hemolysis, irritation and other aspects of Hydroxypropyl-beta-cyclodextrin have already been performed; the safety of this drug has been evaluated accurately. Among all the derivatives of beta-cyclodextrin, Hydroxypropyl-beta-cyclodextrin is considered as a type of pharmaceutical excipients with most complete research data and highest medicinal value, and it has been studied in-width and in-depth mostly.
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